One of the most promising trends in the pharmaceutical industry is the implementation of new integrated solutions for process equipment, which incorporate robotic and automated loading and unloading technology. These solutions have been proven to significantly improve performance and productivity, while also helping to reduce operational costs and increase savings across multiple connected machines covering the entire operational phase. This article aims to provide an overview of the key aspects of these new trends, while also exploring the latest advancements in the automatization of the terminal sterilization of prefilled syringes. By staying informed and implementing these cutting-edge solutions, pharmaceutical companies can ensure that they remain at the forefront of this important industry.